|
KMID : 0620920180500030002
|
|
Experimental & Molecular Medicine
2018 Volume.50 No. 3 p.2 ~ p.2
|
|
|
Whither systems medicine?
|
|
Apweiler Rolf
Beissbarth Tim
Berthold Michael R
Bluthgen Nils
Burmeister Yvonne
Dammann Olaf
Deutsch Andreas
Feuerhake Friedrich
Franke Andre
Hasenauer Jan
Hoffmann Steve
Hofer Thomas
Jansen Peter LM
Kaderali Lars
Klingmuller Ursula
Koch Ina
Kohlbacher Oliver
Kuepfer Lars
Lammert Frank
Maier Dieter
Pfeifer Nico
Radde Nicole
Rehm Markus
Roeder Ingo
Saez-Rodriguez Julio
Sax Ulrich
Schmeck Bernd
Schuppert Andreas
Seilheimer Bernd
Theis Fabian J
Vera Julio
Wolkenhauer Olaf
|
|
|
Abstract
|
|
|
|
New technologies to generate, store and retrieve medical and research data are inducing a rapid change in clinical and translational research and health care. Systems medicine is the interdisciplinary approach wherein physicians and clinical investigators team up with experts from biology, biostatistics, informatics, mathematics and computational modeling to develop methods to use new and stored data to the benefit of the patient. We here provide a critical assessment of the opportunities and challenges arising out of systems approaches in medicine and from this provide a definition of what systems medicine entails. Based on our analysis of current developments in medicine and healthcare and associated research needs, we emphasize the role of systems medicine as a multilevel and multidisciplinary methodological framework for informed data acquisition and interdisciplinary data analysis to extract previously inaccessible knowledge for the benefit of patients.
|
|
|
KEYWORD
|
|
|
Computational models, Translational research
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
    
|